(Characters whose names are bolded here are iconic characters) These are the female characters who are protagonists or playable characters for the majority of the time. (Characters whose names are bolded are characters that are/were protagonists or playable for most of at least one of the games they were featured in.)
Feel free to add more characters and categories! Here is a list of female characters in video games.
10 Anthropomorphic/Non-Human Female Characters.7 Anti-Heroes and the Morally Ambiguous.1 Here is a list of female characters in video games.